The River Island store in Surrey Quays shopping centre is one of 33 stores across the UK set to close before January 2026.
As part of its restructuring plan, the retailer revealed in August that it would reduce its number of stores to avoid collapsing into administration.
Surrey Quays shopping centre is earmarked to be demolished as part of the Canada Water Masterplan.
Despite this, a number of retailers remain open at the site, and a new British Heart Foundation store opened there in October.
Along with the closures, River Island will also pay reduced rent at a further 71 shops.
The outlet currently have 220 stores across the UK and Ireland and employ around 5,500 people.
The other London location set to close is Beckton in East London.
This follows the closure in Southside Shopping Centre in Wandsworth in September.
River Island chief executive Ben Lewis said: “River Island is a much-loved retailer, with a decades-long history on the British high street.
Relatedarticles
“However, the well-documented migration of shoppers from the high street to online has left the business with a large portfolio of stores that is no longer aligned to our customers’ needs.
“The sharp rise in the cost of doing business over the last few years has only added to the financial burden.”
